Five people sustained minor injuries while four firefighters have also been hurt in the course of duty.
KZN Emergency Medical Services says a factory worker is among those injured.
It is unclear what caused the fire which erupted early this morning.
A thick cloud of smoke spirals from the building as firefighters work furiously to prevent the flames from spreading to the neighbouring Plascon building.
Small crowds are gathered across the road watching the fire fighting operation.
Meanwhile Metro police have cordoned off the area. They have closed off both Grimsby and Kenyon Howden Roads to motorists.